In 2010, Dyax also entered into an agreement with CMIC Co., Ltd to commercialize Kalbitor for the treatment of HAE in Japan.Importantly, Dyax is developing DX 2930, a fully human monoclonal antibody that is an inhibitor of kallikrein that was discovered using their phage display platform and is currently in pre clinical development. DX 2930 is expected to be bioavailable via subcutaneous injection and have a long half life that should allow for infrequent dosing. These characteristics make DX 2930 a good potential prophylactic agent for HAE, like ViroPharma’s Cinryze.

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